Will green tea help you lose weight?

Apr. 29, 2013 ? Evidence has shown that green tea extract may be an effective herbal remedy useful for weight control and helping to regulate glucose in type 2 diabetes. In order to ascertain whether green tea truly has this potential, Jae-Hyung Park and his colleagues from the Keimyung University School of Medicine in the Republic of Korea conducted a study, now published in the Springer journal Naunyn-Schmedeberg's Archives of Pharmacology.

The active constituents of green tea, which have been shown to inhibit intestinal glucose and lipid uptake, are a certain type of flavonoid called gallated catechins. The authors had previously suggested that the amount of gallated catechins necessary to reduce blood glucose concentrations can be achieved from a daily dose of green tea. However, the amount of green tea needed to decrease lipid uptake from the gut is higher and has been shown to have adverse effects in humans. Once in the bloodstream, gallated catechins can actually increase insulin resistance, which is a negative consequence especially in obese and diabetic patients.

For their study, the researchers tested the effects of green tea extract on body weight and glucose intolerance in both diabetic mice and normal mice fed a high-fat diet. To prevent a high dose of gallated catechins from reaching the bloodstream, the authors also used a non-toxic resin, polyethylene glycol, to bind the gallated catechins in the gut to prevent their absorption. They then looked at the effects on the mice of eating green tea extract alone, and eating green tea extract plus polyethylene glycol. They compared these against the effects of two other therapeutic drugs routinely prescribed for type 2 diabetes.

Results showed that green tea extract in isolation did not give any improvements in body weight and glucose intolerance. However, when green tea extract was given with polyethylene glycol, there was a significant reduction in body weight gain, insulin resistance and glucose intolerance in both normal mice on a high fat diet and diabetic mice. The polyethylene glycol had the effect of prolonging the amount of time the gallated catechins remained in the intestines, thereby limiting glucose absorption for a longer period.

Interestingly, the effects of the green tea extract in both the intestines and in the circulation were measurable at doses which could be achieved by drinking green tea on a daily basis. In addition, the effects of green tea extract were comparable to those found when taking two of the drugs which are currently recommended for non-insulin dependent diabetes.

The authors conclude that "dietary green tea extract and polyethylene glycol alleviated body weight gain and insulin resistance in diabetic and high-fat mice, thus ameliorating glucose intolerance. Therefore the green tea extract and polyethylene glycol complex may be a preventative and therapeutic tool for obesity and obesity-related type 2 diabetes without too much concern about side effects."

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The above story is reprinted from materials provided by Springer Science+Business Media.

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Journal Reference:

1. Park, Jae-Hyung et al. Green tea extract with polyethylene glycol-3350 reduces body weight and improves glucose tolerance in db/db and high-fat diet mice. Naunyn-Schmiedeberg's Archives of Pharmacology, 2013 DOI: 10.1007/s00210-013-0869-9

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/nutrition/~3/TEmKqINLbLc/130429114739.htm

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Sniffing out schizophrenia

Apr. 29, 2013 ? A debilitating mental illness, schizophrenia can be difficult to diagnose. Because physiological evidence confirming the disease can only be gathered from the brain during an autopsy, mental health professionals have had to rely on a battery of psychological evaluations to diagnose their patients.

Now, Dr. Noam Shomron and Prof. Ruth Navon of Tel Aviv University's Sackler Faculty of Medicine, together with PhD student Eyal Mor from Dr. Shomron's lab and Prof. Akira Sawa of Johns Hopkins Hospital in Baltimore, Maryland, have discovered a method for physical diagnosis -- by collecting tissue from the nose through a simple biopsy. Surprisingly, collecting and sequencing neurons from the nose may lead to "more sure-fire" diagnostic capabilities than ever before, Dr. Shomron says.

This finding, which was reported in the journal Neurobiology of Disease, could not only lead to a more accurate diagnosis, it may also permit the crucial, early detection of the disease, giving rise to vastly improved treatment overall.

From the nose to diagnosis

Until now, biomarkers for schizophrenia had only been found in the neuron cells of the brain, which can't be collected before death. By that point it's obviously too late to do the patient any good, says Dr. Shomron. Instead, psychiatrists depend on psychological evaluations for diagnosis, including interviews with the patient and reports by family and friends.

For a solution to this diagnostic dilemma, the researchers turned to the olfactory system, which includes neurons located on the upper part of the inner nose. Researchers at Johns Hopkins University collected samples of olfactory neurons from patients diagnosed with schizophrenia and a control group of non-affected individuals, then sent them to Dr. Shomron's TAU lab.

Dr. Shomron and his fellow researchers applied a high-throughput technology to these samples, studying the microRNA of the olfactory neurons. Within these molecules, which help to regulate our genetic code, they were able to identify a microRNA which is highly elevated in those with schizophrenia, compared to individuals who do not have the disease.

"We were able to narrow down the microRNA to a differentially expressed set, and from there down to a specific microRNA which is elevated in individuals with the disease compared to healthy individuals," explains Dr. Shomron. Further research revealed that this particular microRNA controls genes associated with the generation of neurons.

In practice, material for biopsy could be collected through a quick and easy outpatient procedure, using a local anesthetic, says Dr. Shomron. And with microRNA profiling results ready in a matter of hours, this method could evolve into a relatively simple and accurate test to diagnose a very complicated illness.

Early detection, early intervention

Though there is much more to investigate, Dr. Shomron has high hopes for this diagnostic method. It's important to determine whether this alteration in microRNA expression begins before schizophrenic symptoms begin to exhibit themselves, or only after the disease fully develops, he says. If this change comes near the beginning of the timeline, it could be invaluable for early diagnostics. This would mean early intervention, better treatment, and possibly even the postponement of symptoms.

If, for example, a person has a family history of schizophrenia, this test could reveal whether they too suffer from the disease. And while such advanced warning doesn't mean a cure is on the horizon, it will help both patient and doctor identify and prepare for the challenges ahead.

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The above story is reprinted from materials provided by American Friends of Tel Aviv University.

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Journal Reference:

1. Eyal Mor, Shin-Ichi Kano, Carlo Colantuoni, Akira Sawa, Ruth Navon, Noam Shomron. MicroRNA-382 expression is elevated in the olfactory neuroepithelium of schizophrenia patients. Neurobiology of Disease, 2013; 55: 1 DOI: 10.1016/j.nbd.2013.03.011

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/strange_science/~3/zHXUhnxaa7s/130429130548.htm

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NBA owner Michael Jordan marries over the weekend

Michael Jordan got married over the weekend in front of a few hundred of his family and closest friends.

The Charlotte Bobcats owner exchanged vows with 35-year-old former model Yvette Prieto on Saturday in Palm Beach, Fla., Jordan's manager Estee Portnoy told The Associated Press Sunday

The wedding took place at the Episcopal Church of Bethesda-by-the-Sea with nearly 300 guests in attendance, including Tiger Woods, Patrick Ewing, Spike Lee and Ahmad Rashad.

The ceremony was followed by a reception at the Bear's Club in Jupiter, Fla., a luxurious private golf club designed by Jack Nicklaus. Jordan, 50, owns a home near the course.

There were fireworks at night as part of the celebration.

In lieu of wedding gifts, donations were made to the James R. Jordan Foundation. The wedding flowers were donated to the Jupiter Medical Center.

The six-time NBA champion and Prieto met five years ago and were engaged last December.

Prieto wore a French silk voile corseted sheer sheath gown by J'Aton Couture, in an ecru palette with accents of flesh tones, with handmade silk lace created especially for her, and enhanced with Swarovski crystals. The gown featured French seamed crinoline borders, which cascaded into a dramatic cathedral train finished in the lace, with accents of a peacock-feathered design.

The couple and their guests were entertained by DJ MC Lyte, singers K'Jon, Robin Thicke and Grammy-Award winner Usher and The Source, an 18-piece band.

Everyone enjoyed an all-white, seven-layer white rum wedding cake that was covered in white fondant and sugar crystals, and adorned with crystal brooches and the couples' monogram on the top layer.

Guests sat at tables that were a continuous candle-lit landscape with a myriad of crystal candelabras and mercury glass vessels, each filled with one variety of white flower, including roses, peonies and tulips, and one accent of purple.

Source: http://news.yahoo.com/nba-owner-michael-jordan-marries-over-weekend-202151649.html

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Rep. Mike Rogers: 'Some Action Needs to be Taken' on Syria (ABC News)

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Lawmaker: FBI checking training angle in bombing

FILE - In this Saturday, April 27, 2013 file photo, visitors pause at a makeshift memorial in Copley Square for victims of the Boston Marathon bombings, in Boston. Rep. Michael McCaul, the chairman of the House Homeland Security Committee, says he believes the Boston Marathon bombing suspects had some training in carrying out their attack. McCaul is citing the type of device used in the attack, the shrapnel-packed pressure-cooker bombs, and the weapons' sophistication as signs of training. (AP Photo/Robert F. Bukaty, File)

FILE - In this Saturday, April 27, 2013 file photo, visitors pause at a makeshift memorial in Copley Square for victims of the Boston Marathon bombings, in Boston. Rep. Michael McCaul, the chairman of the House Homeland Security Committee, says he believes the Boston Marathon bombing suspects had some training in carrying out their attack. McCaul is citing the type of device used in the attack, the shrapnel-packed pressure-cooker bombs, and the weapons' sophistication as signs of training. (AP Photo/Robert F. Bukaty, File)

FILE - In this Tuesday, Nov. 16, 2010 file photo, House Committee on Standards of Official Conduct ranking member Rep. Michael McCaul, R-Texas, arrives for a closed door executive session on Capitol Hill in Washington. McCaul, the chairman of the House Homeland Security Committee, says he believes the Boston Marathon bombing suspects had some training in carrying out their attack. McCaul is citing the type of device used in the attack, the shrapnel-packed pressure-cooker bombs, and the weapons' sophistication as signs of training. (AP Photo/Cliff Owen, File)

FILE - This file image from a Federal Bureau of Investigation and Department of Homeland Security joint bulletin issued to law enforcement and obtained by The Associated Press, shows the remains of a pressure cooker that the FBI says was part of one of the bombs that exploded during the Boston Marathon. Rep. Michael McCaul, the chairman of the House Homeland Security Committee, says he believes the Boston Marathon bombing suspects had some training in carrying out their attack. McCaul is citing the type of device used in the attack, the shrapnel-packed pressure-cooker bombs, and the weapons' sophistication as signs of training. (AP Photo/FBI, File)

WASHINGTON (AP) ? The chairman of the House Homeland Security Committee said Sunday that the FBI is investigating in the United States and overseas to determine whether the suspects in the Boston Marathon bombing received training that helped them carry out the attack.

Dzhokhar Tsarnaev, 19, is charged with joining with his older brother, Tamerlan, who's now dead, in setting off the shrapnel-packed pressure-cooker bombs. The bombs were triggered by a remote detonator of the kind used in remote-control toys, U.S. officials have said.

U.S. officials investigating the bombings have told The Associated Press that so far there is no evidence to date of a wider plot, including training, direction or funding for the attacks.

A criminal complaint outlining federal charges against Dzhokhar Tsarnaev described him as holding a cellphone in his hand minutes before the first explosion.

The brothers are ethnic Chechens from Russia who came to the United States about a decade ago with their parents.

"I think given the level of sophistication of this device, the fact that the pressure cooker is a signature device that goes back to Pakistan, Afghanistan, leads me to believe ? and the way they handled these devices and the tradecraft ? ... that there was a trainer and the question is where is that trainer or trainers," said Rep. Michael McCaul, R-Texas, on "Fox News Sunday."

"Are they overseas in the Chechen region or are they in the United States?" McCaul said. "In my conversations with the FBI, that's the big question. They've casted a wide net both overseas and in the United States to find out where this person is. But I think the experts all agree that there is someone who did train these two individuals."

Rep. Adam Schiff, D-Calif., a member of the House Intelligence Committee, said he thought it's "probably true" that the attack was not linked to a major group. But, he told CNN's "State of the Union," that there "may have been radicalizing influences" in the U.S. or abroad. "It does look like a lot of radicalization was self-radicalization online, but we don't know the full answers yet."

On ABC's "This Week," moderator George Stephanopoulos raised the question to the chairman of the House Intelligence Committee about FBI suspicions that the brothers had help in getting the bombs together.

"Absolutely, and not only that, but in the self-radicalization process, you still need outside affirmation," responded Rep. Mike Rogers, R-Mich.

"We still have persons of interest that we're working to find and identify and have conversations with," he added.

At this point in the investigation, however, Sen. Claire McCaskill said there was no evidence that the brothers "were part of a larger organization, that they were, in fact, part of some kind of terror cell or any kind of direction."

The Missouri Democrat, who's on the Senate Homeland Security and Governmental Affairs Committee, told CBS' "Face the Nation" that "it appears, at this point, based on the evidence, that it's the two of them."

Homemade bombs built from pressure cookers have been a frequent weapon of militants in Afghanistan, India and Pakistan. Al-Qaida's branch in Yemen once published an online manual on how to make one.

Tamerlan Tsarnaev was an ardent reader of jihadist websites and extremist propaganda, officials have said. He frequently looked at extremist sites, including Inspire magazine, an English-language online publication produced by al-Qaida's Yemen affiliate.

In recent years, two would-be U.S. attackers reported receiving bomb-making training from foreign groups but failed to set off the explosives.

A Nigerian man was given a mandatory life sentence for trying to blow up a packed jetliner on Christmas Day 2009 with a bomb sewn into his underwear. Umar Farouk Abdulmutallab had tried to set off the bomb minutes before the Amsterdam-to-Detroit flight landed.

The device didn't work as planned, but it still produced smoke, flame and panic. He told authorities that he trained in Yemen under the eye of Anwar al-Awlaki, a radical American-born cleric and one of the best-known al-Qaida figures.

A U.S. drone strike in Yemen killed al-Awlaki in 2011.

In 2010, a Pakistani immigrant who tried to detonate a car bomb in New York's Times Square also received a life sentence. Faisal Shazad said the Pakistan Taliban provided him with more than $15,000 and five days of explosives training.

The bomb was made of fireworks fertilizer, propane tanks and gasoline canisters. Explosives experts said the fertilizer wasn't the right grade and the fireworks weren't powerful enough to set off the intended chain reaction.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-04-28-Boston%20Marathon-Congress/id-8a6376da8014442fa115039bb649d7bc

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95% Gimme The Loot

All Critics (41) | Top Critics (22) | Fresh (39) | Rotten (2)

A thousand-watt jolt of mischief, a spunky, funky, ebullient indie that packs its 81 minutes with cinematic exhilaration.

It may be a slight movie, but it has its sunny charms.

A movie about teenage taggers in the Bronx should be fast and raw, scruffy and loose, and Adam Leon's Gimme the Loot is just that.

As it lopes along, the movie offers a warm but very sharp portrait of New York's have-nots and their uneasy relationship with the haves.

"Gimme the Loot" shouldn't be as appealing and exuberant as it is, it really shouldn't.

Tashiana Washington and Ty Hickson are terrific in the main roles. So is Zo? Lescaze as Ginnie, a spoiled white kid who teaches the taggers a thing or two about drift and being dissolute.

A slim, low-budget coming-of-age tale whose richness lies entirely in its interstices. A keenly observed work that celebrates the unfettered joys of youth, and rewards by reminding of the power of a simple tale told well.

Simultaneously real and hopeful, "Loot" has almost no plot, but when the setting is so fresh and the characters feel so raw and alive, who needs one?

Ghetto laughs with a sophisticated point of view.

...a magical, summery treat.

Promotes robbery and can't be serious in expecting us to care whether Malcolm and Sofia become more than friends.

The winner of the Indie Spirit 'One to Watch' award could never work again and will always have a memorable New York City film to his credit.

An impressive debut feature, Gimme the Loot is also an unusual take on characters who want to leave their stamp on "the city that never sleeps."

Much more grownup than it looks, Gimme the Loot is that rare teen-centric film whose brisk pace is unburdened by sentimentality.

Writer-director Adam Leon has crafted a classic New York story, a film imbued with the fast rhythms and muggy sensations of city life during the summer.

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Source: http://www.rottentomatoes.com/m/gimme_the_loot_2012/

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Earth's cooling came to sudden halt in 1900, study shows

An international study used tree rings and pollen to build the first?record of global climate change, continent by continent, over 2,000 years.

By Pete Spotts,?Staff writer / April 23, 2013

Emperor penguins walk across sea ice near Ross Island, Antarctica, in this 2012 photo released by Thomas Beer. The continent's pristine habitat provides a laboratory for scientists studying the effects of climate change.

Courtesy Thomas Beer/AP/File

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A reconstruction of 2,000 years of global temperatures shows that a long-term decline in Earth's temperatures ended abruptly about 1900, replaced by a warming trend that has continued despite the persistence into the 20th century of the factors driving the cooling, according to a new study.

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Indeed, for several continents, the increase in global average temperatures from the 19th century to the 20th was the highest century-to-century increase during the 2,000-year span, the study indicates. It's the first study to attempt building a millennial-scale climate history, continent by continent.

The research wasn't designed to identify the cause of the warming trend, which climate researchers say has been triggered by a buildup of greenhouse gases ? mainly carbon dioxide ? as humans burned increasing amounts of fossil fuel and altered the landscape in ways that released CO2.

Still, it's hard to explain 20th-century warming without including the influence of rising CO2 levels, because the factors driving the cooling were still present, notes Darrell Kaufman, a researcher at Northern Arizona University and one of the lead authors on the paper formally reporting the results in the journal Nature Geoscience.

The study, five years in the making, drew on the work of 87 scientists in 24 countries as part of the International Geosphere-Biosphere Program. One goal of the 27-year-old program is to gain a deeper understanding of Earth's climate history and the factors that contribute to climate variability.

The study used nature's proxies for thermometers ? tree rings, pollen, and other natural temperature indicators ? to build continent by continent a coordinated record of temperature changes during the past two millenniums.

Scientists use this proxy approach to reach further into the climate's temperature history than the relatively short thermometer record allows. Such efforts aim to put today's climate into a deeper historical context as well as to identify the duration and possible triggers for natural swings that the climate undergoes over a variety of time scales.

Last March, for instance, a team led by Shaun Marcott at Oregon State University used climate proxies to build a global temperature record reaching back 1,200 years ? one that also noted the pre-1900 cooling trend.

Until now, however, the proxy approach has been used to reconstruct changes in global-average and hemisphere-wide temperatures, Dr. Kaufman explains.

"There was very little information about past climate variability at the regional scale," he says. Yet the team notes that no one lives in a global-average world. People live in specific regions where geography plays a vital role in shaping the climate patterns they experience.

Source: http://rss.csmonitor.com/~r/feeds/science/~3/s_CQlowEYIE/Earth-s-cooling-came-to-sudden-halt-in-1900-study-shows

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Details of Boston carjacking victim's ordeal comes out in Globe interview

>> we will revisit this.

>>> chilling details surrounding the tsarnaev brothers alleged plot to attack the heart of new york city after causing so much damage in boston . according to city officials, the two marathon bombing suspects discussed driving to new york to detonate their remaining explosives in a spontaneous assault on times square . at the time, their arsenal included five pipe bombs and one pressure cooker bomb similar to the ones used in last monday's deadly attack. police say the younger brother had visited times square once last year but their plan fell apart after realizing the mercedes-benz car they hijacked did not have enough car to get to new york . a pre- miranda rights interrogation of 19-year-old dzhokhar tsarnaev it appears the younger brother has stopped answering questions about the bombing since he was read his rights on monday night and that has sparked a debate among lawmakers how the government should handle domestic terror cases.

>> we can't have, in a case like than, the judiciary deciding because it's on tv and it might look bad for them to allow the public safety exemption that is deemed legal by the united states supreme court that they would somehow intercede in this, it is confusing and it's horrible god awful policy and danger to the greater community and we have got to get to the bottom of this and we have got to fix it right now.

>> tsarnaev was reportedly questioned by investigators up to 16 hours over the course of two days and answering questions mostly in writing due to the severe injury to his neck.

>> jane harman , there would be some people that would look at the fact that the plot in times square was foiled because they didn't have enough gas in their tank to get down to new york as a sign -- as a good sign that this was half-baked plot. it actually scares me that guys -- this ill-prepared could be running around with bombs. it's the sort of thing you're not going to pick up chatter. you're not going to pick up any clues from overseas. this is a sort of a random violence that we should all really be child by even more so than if they had some contacts overseas.

>> i agree. mike hayden said the other day, the former director of the cia , that this is the new normal. in this case, i think we will learn that some mistakes were made. we should have been on these guys earlier than we were, but this type of thing, self-radicalized people, in this case, maybe this fellow misha had a lot to do with radicalizing these kids. self-radicalized people who go on the internet and you can find the recipe for building pressure cooker bombs or pipe bombs or other kinds of small weapons can maybe sometimes get lucky and pull it off in this country. they have to be right once. we have to be right 100% of the time but on something that mika said just before, joe, she said mike rogers , among other things, perhaps, are complaining that this fellow was mirandaized. a liberal named george will had an op-ed in "the washington post " yesterday talking about incarcerating the japanese during world war ii and made the point if we live by our values and we follow the rule of law, we do better and, in this case, i think when we look back on all of this, the way we handled the investigation and the prosecution of this fellow who for sure, i think based on the evidence we know who likely will be convicted, will be a model for the world and it will show people that we followed the rule of law here and that is what we have to do.

>> as congresswoman harmon is talking we are getting word that dzhokhar tsarnaev has been transported from beth israel hospital to prison. we are talking about his physical condition. apparently it's upgraded to the point they have taken him out of the hospital new and he has been moved to a prison in massachusetts. one of the people we haven't talked about a lot but we have heard about is this guy who was car-jacked a week ago. he is a 26-year-old chinese man in this black mercedes suv and come to boston to go to grad school and now working on a start-up. he lives in boston . he gets car-jacked around 11:00 last thursday night and taken on an interview with "the boston globe " a 90-minute ride. remember it was reported 30 minutes ? he says it's 90-minute ride. you have to talk about this key to these two brothers being caught. he said finally after this 90 minutes they realized they don't have enough gas to get to manhattan and pull up to a gas station and turns out it's cash only. so they have to go inside. one of the brothers has to go inside the gas station to pay. at that point, this guy who calls himself danny, didn't want to give his real name, makes a decision even though the other brother is in the back seat that is going to bolt. this is life and death . he unbuckles the seat belt and he said he ran in an angle that would be hard for the brother to shoot him. he runs across the street to another gas station and tells the attendant to call 911. he left his iphone in the car so it could be tracked and traced. it's a remarkable account if you have a chance to read "the boston globe " about two and a half hour interview where he gives a moment-by-moment recap and he is critical to these two guys being caught.

>> no doubt. that is when everything started unraveling for them and there was even the moment where his friend kept calling him up and he said if you speak in mandarin, i'm going to kill you right here. you get to the part where the brother was doing an english mandarin translation to tell him what to text back to his friend and the guy just kept his head and was responsible for these two terrorists being caught.

>> the reason the i phone was left in the car? the two brothers wanted to listen to music so he plugged in his iphone to the car.

>> oh, my lord!

>> so the phone was not on his body, it was plugged into the car.

>> runs across the street to a mob mobil station and they call 911.

>> it speaks to a new normal which congresswoman harman was touching on. i find your sentiment far more alarming than anything else. deval patrick , the governor, i thought handled it so well. he said the next day the young tsarnaev went to school and went to the gym and paertrtied with friends as if nothing had happen. going forward for law enforcement , how do you track this and what steps to prevent this from going forward? an e in the course challenge for law enforcement and intelligence officials going forward.

>> one of the tragedies, though, is president kennedy saw this. he said if someone wants to trade their life for mine, no way i can be protected. men with guns change history, whether it's sarajevo or memphis in 1968 . the day before, you broke in and you said this guy, these people are going to do than, everybody would go, come on, they could never pull this off, but they did.

>> jane?

>> yeah. the nypd has a lot of tools that other local police departments may have to learn about. of course, new york is a much bigger target and so is washington. perhaps than boston or someplace in the midwest. but they have a thousand intelligence officers . they have a huge police department . 35,000 people compared to 2,000 in boston . i think that's the number. obviously, a bigger population. but they can detect signs early. for example the older brother was thrown out of his mosque and there was behavior there they would pick up because they built trust with the muslim community . let's be clear that all would-be radicalized people are not muslim but nonetheless they can pick up signs and follow these people much more closely and they have thwarted a lot of plots. we have been successful more than we have failed in blocking plots against our country.

>> yes.

>> and these small bore plots, i know a lot of people were hurt but this is nothing like 9/11, are going to be in our future and if we have better intel in our local police departments, we're going to do better getting ahead of the curve, even with people like this who are substantially invisible.

>> jane harman , thank you so much. on monday, we will be marking six months since superstorm sandy devastated the eastern seaboard . we will be live from some of the hardest hit spots and see how they are recovering.

>>> coming up, mike florio will join us to break down the nfl draft .

>> thanks, willie.

>> trickalso chemical war fare in syria. richard haass weighs in on the significant developments in that conflict. chadwick boseman describes his role as the great jackie robinson .

>> great movie.

>> a new article "the atlantic" says changing technology means we may never run out of oil. james bennett is here to explain.

>> there you go!

>> the top stories coming up next and the political playbook.

>>> first, bill karins with a check on the forecast. bill?

>> good morning. it's a nice happy forecast for so many people in this country as we head to a nice, warm weekend for once. just about everywhere on the map. we are going to have some rain to deal with but first recap yesterday. one of the warmest days we have seen in montana, colorado through the central plains . it was beautiful. the last spot to warm up is minneapolis, north wards and up through the great lakes. that warm air coming your way this weekend. we do have a little bit of rain this morning. kansas city and st. louis that's going to head for louisville, nashville, memphis, little rock and tulsa during the day today so you need your umbrellas. tomorrow a lot of that rain will be in kentucky and tennessee. although it's warm, it will be, unfortunately, a little bit wet. here is your forecast into the weekend. starting with today, another great day from new york to boston to d.c. it is a little chilly in the northeast this morning but this afternoon, perfect. then the weekend forecast look at minneapolis. about time! 72 warm degrees! you're going to be the same temperature as atlanta because the southeast you're going to be dodging the raindrops all weekend long and maybe even a few thunderstorms mixed in too and wrap it up with your sunday forecast and notice kansas city , you deserve that after the spring you had. 74 and sunny beautiful degrees! overall, this is a thumb's up weekend. the only exception being the rain in the southeast. you're watching " morning joe ," brewed by starbucks.

Source: http://feeds.nbcnews.com/c/35002/f/653381/s/2b35495f/l/0Lvideo0Bmsnbc0Bmsn0N0Cid0C51672911/story01.htm

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France's Hollande to ease entrepreneurs' capital gains tax

PARIS (Reuters) - President Francois Hollande will propose next week easing entrepreneurs' capital gains tax, an official in his office told French media on Friday, as the Socialist leader struggles to win the confidence of business owners.

Hollande's government had planned last year to raise capital gains tax on business owners early in its mandate, but backed down after a high-profile revolt and warnings the move would drive start-up companies abroad.

But the episode, and increases in other business taxes, have created a climate of mistrust for the government among business owners at a time when leaders need them to help kick-start the stagnant economy and create jobs.

Eager to dispel the bad blood, Hollande is set to announce plans to reduce the taxable amount of their capital gains by up to 65 percent, Les Echos business newspaper reported on its website on Friday.

Under special cases such as a business owner retiring, the deduction could reach as much as 85 percent, the daily said.

The presidency official did not confirm the numbers but insisted that Hollande wanted to encourage businesses to be set up and help risk-taking investors that finance new firms.

With the thinnest profit margins in the euro zone, corporate confidence has fallen to levels not seen since the 2008-2009 financial crisis as firms face plunging demand and high taxes.

Hollande's Socialist government is struggling to win back corporate France's confidence, with many business people fearing more tax hikes are in store as the state battles to bring down its budget deficit.

Prime Minister Jean-Marc Ayrault acknowledged last week that the government's flagship measure for companies, a tax credit aimed at cutting their wage bill indirectly, had received a tepid reception so far.

(Reporting by Elizabeth Pineau; Writing by Leigh Thomas)

Source: http://news.yahoo.com/frances-hollande-ease-entrepreneurs-capital-gains-tax-185738819.html

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Military grooms new officers for war in cyberspace

AIR FORCE ACADEMY, Colo. (AP) ? The U.S. service academies are ramping up efforts to groom a new breed of cyberspace warriors to confront increasing threats to the nation's military and civilian computer networks that control everything from electrical power grids to the banking system.

Students at the Army, Navy and Air Force academies are taking more courses and participating in elaborate cyberwarfare exercises as the military educates a generation of future commanders in the theory and practice of computer warfare.

The academies have been training cadets in cyber for more than a decade. But the effort has taken on new urgency amid warnings that hostile nations or organizations might be capable of crippling attacks on critical networks.

James Clapper, director of national intelligence, called cyberattack the top threat to national security when he presented the annual Worldwide Threat Assessment to Congress this month. "Threats are more diverse, interconnected, and viral than at any time in history," his report stated. "Destruction can be invisible, latent, and progressive."

China-based hackers have long been accused of cyber intrusions, and earlier this year the cybersecurity firm Mandiant released a report with new details allegedly linking a secret Chinese military unit to years of cyberattacks against U.S. companies. This year, The New York Times, The Wall Street Journal and The Washington Post all reported breaches in their computer systems and said they suspected Chinese hackers. China denies carrying out cyberattacks.

On Tuesday, hackers compromised Associated Press Twitter accounts and sent out a false tweet. AP quickly put out word that the report was false and that its accounts had been hacked. AP's accounts were shut down until the problem was corrected.

Once viewed as an obscure and even nerdy pursuit, cyber is now seen as one of the hottest fields in warfare ? "a great career field in the future," said Ryan Zacher, a junior at the Air Force Academy outside Colorado Springs, Colo., who switched from aeronautical engineering to computer science.

Last year the U.S. Naval Academy in Annapolis, Md., began requiring freshmen to take a semester on cybersecurity, and it is adding a second required cyber course for juniors next year.

The school offered a major in cyber operations for the first time this year to the freshman class, and 33 midshipmen, or about 3 percent of the freshmen, signed up for it. Another 79 are majoring in computer engineering, information technology or computer science, bringing majors with a computer emphasis to about 10 percent of the class.

"There's a great deal of interest, much more than we could possibly, initially, entertain," said the academy's superintendent, Vice Adm. Michael Miller.

Since 2004, the Air Force Academy has offered a degree in computer science-cyberwarfare ? initially called computer science-information assurance ? that requires cadets to take courses in cryptology, information warfare and network security in addition to standard computer science. The academy is retooling a freshman computing course so that more than half its content is about cyberspace, and is looking into adding another cyber course.

"All of these cadets know that they are going to be on the front lines defending the nation in cyber," said Martin Carlisle, a computer science professor at the Air Force Academy and director of the school's Center for Cyberspace Research.

About 25 Air Force cadets will graduate this year with the computer science-cyberwarfare degree, and many will go on to advanced studies and work in their service's cyber headquarters or for U.S. Cyber Command at Fort Meade, Md., the Defense Department command responsible for defensive and offensive cyberwarfare.

Almost every Army cadet at the U.S. Military Academy at West Point, N.Y., takes two technology courses related to such topics as computer security and privacy. West Point also offers other cyber courses, and a computer security group meets weekly. One of the biggest cybersecurity challenges is keeping up with the head-spinning pace of change in the field.

"You know American history is pretty much the same" every year, said Lt. Col. David Raymond, who teaches a cybersecurity course. "In this domain, it's really tough to keep up with how this thing evolves."

In his congressional report, Clapper noted that the chance of a major attack by Russia, China or another nation with advanced cyber skills is remote outside a military conflict ? but that other nations or groups could launch less sophisticated cyberattacks in hopes of provoking the United States or in retaliation for U.S. actions or policies overseas. South Korea accused North Korea of mounting a cyberattack in March that shut down thousands of computers at banks and television broadcasters.

Gen. Keith Alexander, head of U.S. Cyber Command, told Congress in March the command is creating teams to carry out both offensive and defensive operations. A spokesman said the command is drawing cyber officers from the service academies, officer schools and Reserve Officer Training Corps programs.

Teams from the three academies compete in events such as last week's National Security Agency Cyber Defense Exercise, in which they try to keep simulated computer networks running as an NSA "aggressor team" attacks. Teams from the U.S. Coast Guard and Merchant Marine academies also took part, along with graduate students from the U.S. Naval Postgraduate School and Canada's Royal Military College.

Air Force won among undergraduate schools. The Royal Military College won among graduate schools.

That hands-on experience is invaluable, said 2nd Lt. Jordan Keefer, a 2012 Air Force Academy graduate now pursuing a master's degree in cyberoperations at the Air Force Institute of Technology.

"You can't just go out there and start hacking. That's against the law," he said. The competitions, he said, "gave me actual experience defending a network, attacking a network."

Counterterrorism expert Richard Clarke, noting that really high-level computer skills are rare, suggested the military might have to re-examine some of its recruiting standards to attract the most adept cyberwarriors.

"Hackers are the 1 percent, the elite and the creators," said Clarke, who served as White House cybersecurity adviser during the Clinton administration. "I wouldn't worry a whole heck of a lot (about whether they) can they run fast or lift weights."

Cyber's appeal was enough to get Keefer to put aside his dream of becoming a fighter pilot, a job with undeniable swagger. "It's a challenge, and for people who like a challenge, it's the only place to be," Keefer said.

___

Witte reported from Annapolis, Md. Associated Press Writer Michael Hill in Albany, N.Y., contributed to this report.

___

Follow Dan Elliott at http://twitter.com/DanElliottAP. Follow Brian Witte at http://twitter.com/APBrianWitte . Follow Michael Hill at http://twitter.com/MichaelTHill

Source: http://news.yahoo.com/military-grooms-officers-war-cyberspace-083354456.html

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Stephen Wolfram says he almost had a deal with Google, but it 'blew up'

As you may recall, Wolfram Research signed a deal with Microsoft a few years back that saw some Wolfram Alpha functionality integrated into Bing. As it turns out, it very nearly found its way into a certain other search engine as well. In an interview at The Next Web conference in Amsterdam today, Stephen Wolfram revealed that his company had tried to work with Google and "almost had a deal," but it "blew up." Unfortunately, he didn't provide any further details about when those talks took place or exactly what the potential deal entailed, and it doesn't sound like we can expect that deal to revived anytime soon -- especially considering Google's own efforts that are increasingly overlapping with Wolfram Alpha. As Wolfram himself notes, though, the two companies do have something of a longstanding connection: Google co-founder Sergey Brin was actually an intern at Wolfram way back in 1993.

Filed under: Internet

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Source: The Next Web

Source: http://www.engadget.com/2013/04/27/wolfram-alpha-google-deal-blew-up/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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Roundworm quells obesity and related metabolic disorders

Apr. 25, 2013 ? Researchers at the University of Maryland School of Medicine, Baltimore, have shown in a mouse model that infection with nematodes (also known as roundworms) can not only combat obesity but ameliorate related metabolic disorders. Their research is published ahead of print online in the journal Infection and Immunity.

Gastrointestinal nematodes infect approximately 2 billion people worldwide, and some researchers believe up until the 20th century almost everyone had worms. In developed countries there is a decreasing incidence of nematode infection but a rising prevalence of certain types of autoimmunity, suggesting a relationship between the two. Nematode infection has been purported to have therapeutic effects and currently clinical trials are underway to examine worms as a treatment for diseases associated with the relevant cytokines, including inflammatory bowel disease, multiple sclerosis, and allergies.

In the study researchers tested the effect of nematode infection on mice fed a high-fat diet. Infected mice of normal girth gained 15 percent less weight than those that were not infected. Mice that were already obese when infected lost roughly 13 percent of their body weight within 10 days. Infection also drastically lowered fasting blood glucose, a risk factor for diabetes, and reduced fatty liver disease, decreasing liver fat by ~25 percent, and the weight of the liver by 30 percent.

The levels of insulin and leptin also dropped, "indicating that the mice restored their sensitivities to both hormones," says corresponding author Aiping Zhao of the University of Maryland School of Medicine, Baltimore. Leptin moderates appetite. As with too much insulin, too high a level of leptin results in insensitivity, thus contributing to obesity and metabolic syndrome, Zhao explains.

The mechanism of the moderation of these hormones "was associated with a parasite-induced reduction in glucose absorption in the intestine, reduced liver triglycerides, and an increase in the population of cells called "alternatively activated macrophages," which regulate glucose metabolism and inflammation," says coauthor Joe Urban of the United States Department of Agriculture. Some of these changes involved "a protein called interleukin-13 and related intracellular signaling mechanisms," he says. "This suggests that there are immune related shifts in metabolism that can alter expression of obesity and related metabolic syndrome."

The incidence of obesity has been climbing dramatically, worldwide. It is a key risk factor for many metabolic diseases, including diabetes, hypertension, and heart disease. Recent studies indicate that it is accompanied by chronic low-grade inflammation in adipose tissues, causing the release of proinflammatory cytokines and chemokines that contribute to the development of cardiovascular disease and metabolic syndrome.

Parasitic nematode infection induces a marked elevation in host immune Th2-cells and related type 2 cytokines which, besides combating the infection, also have potent anti-inflammatory activity, according to the report.

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Journal Reference:

1. Z. Yang, V. Grinchuk, A. Smith, B. Qin, J. A. Bohl, R. Sun, L. Notari, Z. Zhang, H. Sesaki, J. F. Urban, T. Shea-Donohue, A. Zhao. Parasitic Nematode-Induced Modulation of Body Weight and Associated Metabolic Dysfunction in Mouse Models of Obesity. Infection and Immunity, 2013; DOI: 10.1128/IAI.00053-13

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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/BtOQmRTqrHQ/130425164504.htm

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Ecology buys time for evolution: Climate change disrupts songbird's timing without impacting population size (yet)

Apr. 25, 2013 ? Songbird populations can handle far more disrupting climate change than expected. Density-dependent processes are buying them time for their battle. But without (slow) evolutionary rescue it will not save them in the end, says an international team of scientists led by the Netherlands Institute of Ecology (NIOO-KNAW) in Science this week.

Yes, spring started late this year in North-western Europe. But the general trend of the four last decades is still a rapidly advancing spring. The seasonal timing of trees and insects advance too, but songbirds like Parus major, or the great tit, lag behind. Yet without an accompanying decline in population numbers, it seems, as the international research team shows for the great tit population in the Dutch National Park the Hoge Veluwe.

"It's a real paradox," explain Dr Tom Reed and Prof Marcel Visser of the Netherlands Institute of Ecology. "Due to the changing climate of the past decades the egg laying dates of Parus major have become increasingly mismatched with the timing of the main food source for its chicks: caterpillars. The seasonal timing of the food peak has advanced over twice as fast as that of the birds and the reproductive output is reduced. Still, the population numbers do not go down." On the short term, that is, as Reed, Visser and colleagues from Norway, the USA, and France have now calculated using almost 40 years of data from this songbird.

The solution to the paradox is that although fewer offspring now fledge due to food shortage, each of these chicks has a higher chance of survival until the next breeding season. "We call this relaxed competition, as there are fewer fledglings to compete with," first author Reed points out. Out of 10 eggs laid, 9 chicks are born, 7 fledge and on average only one chick survives winter. That last number increases with less competitors around.

This is the first time that density dependence -- a widespread phenomenon in nature -- and ecological mismatch are linked, and it is a real eye-opener. Reed: "It all seems so obvious once you've calculated this, but people were almost sure that mistiming would lead to a direct population decline."

The great tits that lay eggs earlier in spring are more successful nowadays than late birds, which produce relatively few surviving offspring. This leads to increasing selection for birds to reproduce early. But the total number of birds in the new generation stays the same. "That is the second paradox," the researchers state. "Why are population numbers hardly affected, despite the stronger selection on timing caused by the mismatch? The answer is that for selection it matters which birds survive, while for population size it only matters how many survive. Visser: "The mortality in one group can be compensated for by the success in another. But this stretching, this flexibility, is not unlimited."

The mismatch between egg laying period and caterpillar peak in the woods will keep growing, and so will the impact following the temporary rescue, as long as spring temperatures continue to increase. "The density dependence is only buying the birds time, hopefully for evolutionary adaptation to dig in before population numbers are substantially affected," according to Visser. The new findings can help to predict the impact of future environmental change on other wild populations and to identify relevant measures to take. Even rubber bands stretch only so far before they break.

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Note: If no author is given, the source is cited instead.

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Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/uKfjHEgIXbM/130425142348.htm

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Reid pushes sequester replacement plan (Washington Bureau)

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Time lapse of Bush library construction (CNN)

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T-Mobile's HTC One S finally gets its Jelly Bean update

For those who were worried the day would never come -- the T-Mobile (U.S.) HTC One S is finally getting Android 4.1.1. As confirmed in our HTC One S forums, the sizable (675-megabyte) update brings Jelly Bean, with all its bells and whistles, along with any number of bugfixes. (As of this writing, we're waiting on T-Mobile to post the full changelog.)

The update's a Wifi-only deal, so fire up the router and get downloading.

More: HTC One S forums

Source: http://feedproxy.google.com/~r/androidcentral/~3/H-2vkFsb3qU/story01.htm

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Four Realistic Ways to Cut Your Commuting Costs

Last week as I pulled into the gas station, I felt a series of heart palpitations as I read the prices of gas: $4.09, $4.19, $4.29. While I realize this is lower than some people are currently paying in other parts of the country, I couldn?t help but think of the millions of people who are working, in part, simply to pay for the ?luxury? of driving to and from their workplace.

This is a guest post from Quizzle.com.

My guess is that all of us are working for our paycheck for many reasons?none of which include simply handing over a good chunk of it to the gas station. But if you?re stuck with a daunting commute that necessitates multiple fill-ups each month, what can you do to reduce your commuting costs?

Here are some of the methods I?ve employed to drastically cut commuting costs over the years:

Change Your Work Hours

If you?re not working a traditional shift job and you have some flexibility with your scheduling (or an understanding boss), consider negotiating alternate hours outside of the 9-5. Perhaps you could try coming in early and leaving early or coming in late and leaving late (ideally, it?s not coming in early and leaving late!). By switching up your hours, you could avoid a lot of traffic?especially stop and go traffic which absolutely kills your gas mileage.

Partner Up

Carpooling is a great way to save money, be social, and reduce the chance of driving-induced stress (yes, I?m talking about road rage here, people). Even if you only commit to carpooling two days/week, you can reduce your costs for gas as well as the wear and tear on your vehicle.

If you?re thinking about carpooling, reach out to some close co-workers, solicit options via company message boards and email lists, or make an appointment with your HR rep to see what you can do to set up a car/ride sharing program at your work.

Travel With the Masses

I?ll be the first one to admit that I hate public transit?especially during rush hour. The packed trains and disgruntled passengers can leave a lot to be desired, but it?s a phenomenal way to save money on your commuting expenses.

If you live in an urban area, chances are your employer may participate in a reduced fare program. I?ve taken advantage of such a deal through my part-time job as I pay a mere $32/month for an unlimited bus/subway pass thanks to my employer?s generous subsidy. When I think of the hundreds I save each year, those minor hassles with the crowded trains are a bit more palatable.

Consider Radical Alternatives

If none of these options appeal to you or aren?t feasible for your situation, consider a more radical approach. This could mean forgoing the car altogether in favor of a bicycle, petitioning to work from home more often, or it could go as far as changing jobs.

Realistic Ways to Cut Your Commuting Costs | Quizzle

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For more tips and tools to help you manage your home, money and credit?including the most affordable credit monitoring on the web and complete identity theft protection?visit Quizzle.com. Quizzle is a website that provides you with important information about your credit?starting with your credit report and credit score?as well as the tools you need to improve or monitor it, so you can make smart financial decisions. They also show you how your credit impacts your personal finances and give you personalized tips and tools to help you manage it all.

Image remixed from Sergey Peterman (Shutterstock), Next Please Stop (Flickr), and Teosaurio (Flickr).

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Source: http://feeds.gawker.com/~r/lifehacker/full/~3/ahf1GkjbaEs/four-realistic-ways-to-cut-your-commuting-costs-479728266

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